Technologies
(SIS) products
a highly regulated industry that ensures a high level of consumer and product safety.
SIS material is obtained from the intestine in a manner that removes all viable cells, but leaves the naturally fibrous and porous nature of the matrix behind.11 These proprietary processing methods retain the complex architecture and composition of the extracellular matrix, providing not only the structural collagen framework but also the natural non-collagenous ECM components that are essential for cell interaction, function, and ingrowth.11,12
SIS provides a natural scaffold that allows the body to restore itself through site-specific tissue remodeling.
Tissue Remodeling
the renewal of tissue composition, and the reinforcement of structural tissue architecture.13
Recruit
Renew
Reinforce
References
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14. Franklin ME Jr, Trevino JM, Portillo G, Vela I, Glass JL, Gonzalez JJ. The use of porcine small intestinal submucosa as a prosthetic material for laparoscopic hernia repair in infected and potentially contaminated field: a long term follow-up. Surg Endosc. 2008;22(9):1941-1946.
15. Stelly M, Stelly TC. Histology of CorMatrix bioscaffold 5 years after pericardial closure. Ann Thorac Surg. 2013;96(5):e127-e129.
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19. Badylak SF. The extracellular matrix as a scaffold for tissue reconstruction. Sem Cell Dev Biol. 2002;13(5):377-383.